Preclinical CRO Services
Profit from our cell culture experts, abc biopply’s international network of scientists, our connections to manufacturers and suppliers, and get your fully validated protocol along with all the required cell culture components for the spheroids/organoids of your choice. Or simply have our scientist instruct your personnel in 3D CoSeedis™ handling and spheroid/organoid analysis. Our flexibility is your benefit!
Enlarge 3D CoSeedis service pipeline scheme
Development of Predictive Disease Models
abc biopply can support you in the design, setup and implementation of highly predictive and physiologically relevant preclinical disease models. Our experts will build up and validate the model accrding to your requirements and eventually transfer the technology and assays to your facility.
Alternatively, you may profit from abc biopply's service packages and we do all the assays and analyis for you according to predfined and cutom-tailored parameters.
- Adapt and/or optimize protocols for the transfer of cells from 2D to 3D
- Validation and extension of existing protocols and/or applications for various disease models
- Models covering cell lines, primary cells and stem cells
- Design disease models to address cell-to-cell communication
- Design disease models to address organ-to-organ communication
- Design disease models to address complex multi-organ and multi-cellular disease models
Unique 3D CoSeedis™
abc biopply performs all 3D cell culture assays on the proprietary 3D CoSeedis™ technology platform. Unique in-chip assays have been developed that are unsurpassed in terms of both biological relevance and statistical power. Selection of most prominent assays:
- 3D CoSeedis™ Apoptosis in chip Assay
- 3D CoSeedis™ Co-Culture Assay
- 3D CoSeedis™ Cytotoxicity in chip Assay
- 3D CoSeedis™ Dose Response Assay
- 3D CoSeedis™ Drug Efficacy Assay
- 3D CoSeedis™ Tumor Relapse Assay
- 3D CoSeedis™ Histology Assay
- 3D CoSeedis™ Standard Assay
- 3D CoSeedis™ Live Cell Detection in chip Assay
- 3D CoSeedis™ Antibody Penetration Assay
- 3D CoSeedis™ Late Stage Cancer Relapse Assay
- 3D CoSeedis™ Colony Forming in chip Assay
Comprehensive Service Packages
abc biopply systemic and comprehensive service packages that include 3D culture design, spheroid/organoid growth, treatment and analysis and characterization. Some of the most prominent packages in this range are:
- High Content Analysis
- Pharmacokinetics
- Pharmacodynamics
- Off-target Toxicology Testing
- Spatial-omics (IHC/IF, Proteomic, Genomics)
- 3D Genotoxicity
