3D CoSeedis™ - Mass Production of Homogeneous and Uniform Organoids for HTS/HCS Workflows

Easy Mass Production of ultra homogeneous 3D Organoids for High-Throughput Screening

We are excited to share the results of our latest study demonstrating a fast, reliable, and scalable approach to generating highly uniform 3D organoids (>98%) for HTS applications.

Key Highlights:

• Viability: Post-sorting analysis confirmed no loss of cell viability—all wells filled with viable organoids growing as expected.
• Precision: Mis-filled wells (empty or multiple organoids) were <2%, ensuring high accuracy.
• Uniformity: Organoid size variation was as low as 0.01%, delivering exceptional consistency across plates.
• Speed: Sorting 1 organoid from suspension per well in a 384-well plate took <5 minutes per plate—that’s more than 1 organoid per second.
• Scalability: In less than 10 days, a lab assistant can produce ~180,000 organoids, ready for sorting with consistently less ressources.

This study is based out of combining the 3D CoSeedis Multi-Organoid™ platform from abc biopply and the COPAS VISION™ system from Union Biometrica Inc.—a powerful synergy enabling efficient, cost-effective HTS workflows.

Why it matters:
Starting with homogeneous spheroids simplifies sorting, reduces setup time, and minimizes wasted cultures—accelerating drug discovery and screening processes.

Download your copy of the paper here and contact us for further questions and information.