As your trusted preclinical CRO for complex and humanized disease models, we recognize the importance of reliable and reproducible results in advancing scientific discovery throughout the entire preclinical in vitro and in vivo development process. Our comprehensive range of services includes:
- Target Identification and Validation
- Lead Optimization to improve efficacy, selectivity, and pharmacokinetic properties
- Advanced in vitro studies conducted in microphysiological 3D structures (ideally humanized).
- Advanced in vivo studies testing efficacy and safety in a wide range of animal models (ideally humanized) and fully coordinated with the in vitro materials and results.
- ADME
- Toxicology Studies
- Safety Pharmacology
- Bioanalytics analyzing pharmacokinetics and pharmacodynamics.
- Immunohistology: Studying tissue samples to understand the drug’s effects at the cellular level.
- Customized downstream analyses
- Central labs in Europe and Asia
All of these services are meticulously planned and implemented by our team, ensuring you have a single point of contact. This guarantees absolute data integrity and optimal utilization of resources and time.