Humanized Disease Models

Boosting 3D Drug Development Models to ex vivo Level

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abc biopply Drug Efficacy Services

Tumour Relaps Assays, Viability Assays, Cytotoxicity Assays, Cell Viability Assays, and many more...

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3D CoSeedis™

Easy Mass Production of Uniform and Homogenous Spheroids / Organoids for Predictive Disease Modelling

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abc biopply Histology Services

In chip Immunohistochemistry, Immunofluorescence and Histology

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abc biopply 3D Cell Culture Services

Design and Set-up of Preclinical Desease Models and Complex 3D Cell Culture Systems

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abc biopply humanized disease models predict patients reaction to treatment

Our proprietary technology creates hundreds of miniature versions of patient organs in a laboratory setting, using both healthy and diseased tissues. Our innovative models bridges the predictive gap between the lab and the clinic.



We free preclinical models from non-human components whenever possible

Conventional cellular or animal disease models have shown that the predictability of patient response to treatment is severely limited. Great efforts have been made to humanize mouse models to better predict certain aspects of human physiology and immunology. The abc biopply team has made a significant breakthrough in humanizing upstream 3D cell models through the revolutionary and proprietary 3D CoSeedis in chip communication technology™. Thanks to exceptional physiological growth conditions and unique ways of intercellular communication, our models are free from non-human components to the greatest extent possible and allow us to mimic specific organs and tissues in culture over long periods of time. Thus, we successfully bridge the translational gap with unparalleled physiological responses and unique statistical predictive power.

The 3D CoSeedis™ system is a great tool to generate standardized 3D cultures of patient derived ovarian cancer cells. Through this system we were able to quickly implement an ex vivo culture system of patient derived cells with a tremendous potential to be applied in personalized medicine.

Dr. Ricardo Coelho
Ovarian Cancer Research, Department of Biomedicine, University Hospital Basel, Switzerland

So far, I can tell that we are very satisfied. We tried several other tools for spheroid culturing, but this is by far the easiest to handle.

Alessandra Cereghetti
PhD Student, Dept. of Mol. Mech. of Disease, University of Zurich, Switzerland

3D CoSeedis™ convinces through its innovative modularity that allows us to grow cells in 3D aggregates that normally wouldn’t do so. It either supports aggregation through its unique topography or by the ability to grow feeder cells in a physically separated, distant manner. When investigating the response rate of various tumour cells to radiation, the 3D CoSeedis™ System allows us the flexibility and statistics that we need in experiments.

Dr. Peter Frost
CEO and Owner of PeloBiotech GmbH, Germany

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