Rapid Drug Efficacy Check
What is it about
The Rapid Drug Efficacy Check Package delivers in the shortest time possible a most accurate prediction of clinically relevant drug efficacy and dosages during hit validation, lead optimization and the preclinical test phase. It profits from the unique features of the 3D CoSeedis™ in chip technology forming physiologically relevant micro-tissues in statistically significant quantities.
Packages
(One drug - one target)
- Choose a 3D CoSeedis™ tumor model
- 2D Cytotoxicity Assay – Validation of toxicity on chosen cell system
- Design of 3D disease model – Validation of custom tailored 3D cellular disease model
- 3D CoSeedis™ Cytotoxicity in chip Assay – Integration of 680 data points to determine highly accurate IC50 values
- 3D CoSeedis™ Dose Response Assay – Most sensitive determination of drug effects over time to finetune dosage recommendation
Read-out and example data
- Model design and validation
- Transition 2D to 3D
- Physiological target cytotoxicity IC50
- Ex vivo dose response
- Validation of predictiveness with commercial alternative
- Detailed customer defined report
Your benefits
- Time saving: 10 weeks to result
- Cost saving
- Comparable predictiveness to mouse
- 3R: animal free
- Cyclic Process
More packages
- Drug safety
- Target Validation Package
- Personalized efficacy
- Personalized toxicity target and off-target
- Pathway analysis